Montreal, Canada - According to a study conducted by two doctors at the Research Institute of the MUHC and the University of Montreal, 52.4% of patients with disorders of REM sleep behavior develop a neurodegenerative disease in the twelve years after their initial diagnosis.
This study of 93 patients of the Research Center of Sacre-Coeur, a medical center affiliated with the University of Montreal, shows that patients suffering from disorders of REM sleep behavior were 17.7% probability developing a neurodegenerative disease five years after their diagnosis, 40.6% after 10 years, and 52.4% after 12 years. "These results clearly establish a link, and indicate that these sleep disorders might be a predictor of neuro-degenerative diseases," explains Dr. Postuma. For Jacques Montplaisir, founding director of the Center for the Study of sleep: "These patients should be followed medically very carefully: their observations could help define what are the early warning symptoms of diseases such as Parkinson's, Alzheimer's but also, Dementia with Lewy bodies, or multiple system atrophy. "
"These diseases are currently difficult to diagnose with certainty until a very late stage because the doctors lack of data on warning signs. Such a list would therefore represent a valuable in practice," says he. On the other hand, if there are effective treatments against the disorders of REM sleep behavior, these drugs do not delay the development of neuro-degenerative diseases. The research is very active in this area, these patients may represent a relatively near future target of choice for testing the efficacy of new innovative treatments to combat the degeneration of neurons. The behavior disorder REM sleep affects a small percentage of the population. They grow mostly in men after middle age. This is a specific disease should not be confused with insomnia, night terrors or confusional arousals.
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